Essential Genetics: A Genomics Perspective, Fourth Edition: Practice Quizzes

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Title Text: Essential Genetics: A Genomics Perspective, Fourth Edition, Daniel L. Hartl and Elizabeth W. Jones

Please read each question and select your answer from the choices provided. You must complete all of the questions in order to view your results. At the end of each exam, you have the option to e-mail your results to your instructor.

1: What is the base sequence of a DNA strand that is complementary to 5?-CGATTCGG-3? sequence
	A: 5'-GCTAAGCG-3'
	B: 5-CGATTCGG-3?
	C: 5-CCGAATCG-3?
	D: 5'-TAGCCTAT-3'

2: If guanine makes up 13% of the nucleotides in a sample of DNA then adenine would make up what percent of the bases?
	A: 74
	B: 37
	C: 50
	D: 26
	E: 13

3: Which of the following sequences are palindromes?
	A: 5'-TGGCCT-3'
	B: 5'-GGTGG-3'
	C: 5'-AAAAA-3'
	D: 5'-ATAATAAT-3'
	E: 5'-CATAG-3'

4: In a random sequence consisting of equal proportions of all four nucleotides, what is the average distance between consecutive occurrences of the restriction sites for the Tth111 I 5'-GACNNNGTC-3', where N stands for any nucleotide?
	A: 16
	B: 64
	C: 256
	D: 4096
	E: 65536

5: The technique used to separate molecules on the basis of their different rates of movement in an electric field is known as
	A: DNA cloning
	B: Electrophoresis
	C: PCR
	D: Hybridization
	E: DNA sequencing

6: The chemical bonds in DNA by which the sugar components of adjacent nucleotides are linked through the phosphate groups are called
	A: Phosphodiester bonds
	B: Peptide bond
	C: Hydrogen bond
	D: Ionic bond
	E: van der Waals bond

7: A palindrome is a sequence that
	A: Contains only purines
	B: Can be found in multiple origins of replication
	C: Is used as a primer in DNA replication
	D: Reads differently when read from either direction
	E: Is the same when read from either direction

8: Each new DNA strand is initiated by a
	A: Precursor fragment
	B: Short RNA primer
	C: Restriction fragment
	D: Single-stranded DNA-binding protein
	E: Specific DNA primer

9: 5?-TCAG____-3? is a half of a palindromic restriction site. What is the complete sequence?
	A: 5'-TCAGCTGA-3'
	B: 5'-TCAGTCAG-3'
	C: 5'-AGTCGACT-3'
	D: 5'-CTGACTGA-3'

10: The pyrimidine bases are
	A: Cytosine and guanine
	B: Cytosine and adenine
	C: Adenine and guanine
	D: Thymine and guanine
	E: Thymine and cytosine

Optional: Enter your name and your instructor's E-mail address to have your results E-mailed to him or her.
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