Essential Genetics: A Genomics Perspective, Fourth Edition: Practice Quizzes

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Title Text: Essential Genetics: A Genomics Perspective, Fourth Edition, Daniel L. Hartl and Elizabeth W. Jones

Please read each question and select your answer from the choices provided. You must complete all of the questions in order to view your results. At the end of each exam, you have the option to e-mail your results to your instructor.

1: The normal role of the retinoblastoma (RB) protein is
	A: To decrease contact inhibition
	B: Control of the initiation of DNA synthesis
	C: Control telomerase activity
	D: To suppress of the origin recognition complex
	E: Control epigenetic inheritance

2: Progression from one stage of the cell cycle to the next is controlled by
	A: Cyclin-dependent kinase (CDK) complexes
	B: G protein
	C: Centriole
	D: Ras
	E: RNA polymerase processivity

3: The key player in the DNA damage checkpoint is
	A: CDK-complexes
	B: Mdm2
	C: Bax
	D: p53
	E: G protein

4: The normal function of proto-oncogenes is
	A: Activate apoptosis
	B: To promote cell division or to prevet apoptosis
	C: Pevent cell division and promote apoptosis
	D: Prevent cell division
	E: Prevent senescence

5: Uncovering of the recessive allele be various mechanisms is called
	A: Loss of heterozygosity
	B: Gain of function
	C: Loss of function
	D: Maturation
	E: Apoptosis

6: The spindle pole is organized around a small region of clear cytoplasm near the interphase nucleus called the
	A: Chromosome
	B: Kinetochore
	C: Centrosome
	D: Polysome
	E: Autosome

7: Pevention of cell division and promotion of apoptosis is the normal function of
	A: Imprinted genes
	B: X-linked genes
	C: Recessive genes
	D: The proto-oncogenes
	E: The tumor-supressor genes

8: The senescent behavior of normal cells is associated with a loss of the activity of
	A: DNA polymerase
	B: DNA ligase
	C: Centrosome
	D: Telomerase

9: The p53 transcription factor activates apoptosis by activating transcription of
	A: CDK-complexes
	B: G protein
	C: Bax
	D: Anaphase-promoting complex
	E: cdc13

10: Within the organism , tumor cells
	A: Increase contact inhibition
	B: Are clonal
	C: have decreased telomerase activity
	D: Have low DNA polymerase processivity
	E: Are apoptotic

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