Essential Genetics: A Genomics Perspective, Fourth Edition: Practice Quizzes

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Title Text: Essential Genetics: A Genomics Perspective, Fourth Edition, Daniel L. Hartl and Elizabeth W. Jones

Please read each question and select your answer from the choices provided. You must complete all of the questions in order to view your results. At the end of each exam, you have the option to e-mail your results to your instructor.

1: The technique of studying spontanious mutations developed by Joshua and Esther Lederberg is called
	A: Mutagen test
	B: Amber test
	C: Replica plating
	D: Ames test

2: Genetic characteristic often associated with mutations caused by the insertion of a transposable element is
	A: Instability
	B: Target duplication
	C: Ectopic recombination
	D: A and B only
	E: A, B and C

3: An inducible, error-prone system for repair of DNA damage in E.coli is called
	A: Mismatch repair
	B: SOS repair
	C: Excision repair
	D: Postreplication repair
	E: AP repair

4: Among spontaneous base substitutions, the ratio of transitions to transversions is approximately
	A: Three to two
	B: Three to one
	C: Four to one
	D: Two to one
	E: one to one

5: Certain DNA sequences that are more likely to undergo mutation than others are called
	A: RFLPs
	B: Hotspots
	C: STSs
	D: Fragile
	E: Deaminated

6: The threshold of radiation exposure below which mutations are not induced is
	A: 100 sieverts
	B: 10 sieverts
	C: 1 sieverts
	D: 0.1 sieverts
	E: 0 sieverts

7: Probability of incorporating the wrong base per base pair per replication by DNA polymerase is
	A: 0.00001
	B: 0.0001
	C: 0.001
	D: 0.01
	E: 0.1

8: When ionizing radiation interacts with water or with living tissue, it results in formation of highly reactive ions called
	A: Nitrous acid
	B: Pyrimidine dimers
	C: Free radicals
	D: Nucleotide analogs
	E: Alkylating agents

9: The mismatch repair system recognizes the degree of
	A: Misincorporation
	B: Deamination
	C: Methylation
	D: Disintegration
	E: Depurination

10: An inherited autosomal recessive disease caused by a defect in the system that repairs UV light-induced DNA damage is
	A: Oedipina poelzi
	B: Prader-Willi synrom
	C: Fragile X syndrome
	D: Xeroderma pigmentosum
	E: Treponema pallidum

Optional: Enter your name and your instructor's E-mail address to have your results E-mailed to him or her.
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