The fourth volume in this outstanding series of annual updates in oncology, Progress in Oncology 2004 addresses fifteen of the most important “hot topics” in the field. Under the careful direction of Drs. DeVita, Hellman, and Rosenberg, each volume in this exciting series presents concise summaries of the state of the art in cancer basic science and clinical application, written by 15 of the top researchers and clinicians in the world.

As with all the volumes in the series, PIO 2004 covers critical issues in clinical cancer care and research in a scholarly though readable style. Chapters on advances in treatment and diagnosis, including DNA microarrays, growth factor receptors, new applications of thalidomide, and allografting in NHL review the state of the art in these emerging fields. Top experts provide timely overviews of focused ultrasound therapy, hormone therapy for prostate cancer, and CHOP and rituxin for DLCL. In a special surgery section, world-class authorities discuss approaches to rectal cancer. These and other rigorously referenced chapters make PIO 2004 an indispensable new oncology resource.