New chapter on Microbial Systematics and a Survey of the Domains Bacteria and Archaea.

Added MicroFocus boxes throughout!  Some new MicroFocus box topics include:

• Ribosomal RNA Gene Sequencing
• The Risk of Not Vaccinating: Community and Health Care Settings
• All in the Family: rRNAs and Horizontal Gene Transfer
• Viruses Kill Brain Tumors
• And Many More!

Includes a new Section on the Classification of Eukaryotic Organisms in Chapter 11.

Added MicroInquiry boxes throughout!  New MicroInquiry boxes include:

• The Prokaryote/Eukaryote Model
• Mucosal Immunity
• The Pap and HPV Tests
• And More!

New information on allergy tests as well as new information on the replication of HIV is found in Chapter 17.

Chapter 9 includes a new section on metagenomics.

Includes new and expanded coverage of infections of the skin and eye.

New section on the structure and function of the respiratory system is included in Chapter 20.