Foreword
Chapter 1 Prostate Cancer and Molecular Medicine
Jeffrey S. Ross and Gennadi V. Glinsky
Chapter 2 Molecular Diagnostic Techniques in Prostate Cancer
Jeffrey S. Ross
Chapter 3 Molecular Epidemiology of Prostate Cancer
Jeffrey S. Ross
Chapter 4 Prostate Cancer Stem Cells
Jack A. Schalken and Christopher S. Foster
Chapter 5 Prostate Cancer Screening and Chemoprevention
Jacques Baillargeon, Ian Thompson, Javier Hernandez, and David P. Rose
Chapter 6 Molecular Methods, Including Reverse Transcriptase Polymerase Chain Reaction and Proteomics, for Prostate Cancer Screening and Detection of Recurrence and Micrometastasis
Douglas P. Malinowski
Chapter 7 Genomic Classification of Prostate Carcinoma
William L. Gerald
Chapter 8 Pathology of Premalignant Lesions and Adenocarcinoma of Prostate
Minxin Che and Wael A Sakr
Chapter 9 Overview of Prognostic and Predictive Factors in Prostate Cancer
Jeffrey S. Ross, Timothy A. Jennings, Tipu Nazeer, Christine E. Sheehan, Hugh A.G. Fisher, Ronald A. Kauffman, and Bhaskar V.S. Kallakury
Chapter 10 Cytogenetics and Molecular Genetics of Prostate Cancer
Arthur R. Brothman, Teresa M. Maxwell, Joseph Pettus, and Stanford Putman
Chapter 11 DNA Ploidy and S Phase Analysis in Prostate Cancer
Jeffrey S. Ross, Merrill S. Ross, Metin Punar, Ann B. Boguniewicz, Tipu Nazeer, and Timothy Jennings
Chapter 12 Cell Proliferation Markers and Cell Cycle Regulators in Prostate Cancer
Jeffrey S. Ross, Scott E. Eggener, and Carlos Cordon-Cardo
Chapter 13 Targeted Therapies for Cancer: Integrating Diagnostics and Therapeutics
Jeffrey S. Ross
Chapter 14 The Androgen Receptor and Hormone-Based Therapies
Kristin A. Raclaw and Donald J. Tindall
Chapter 15 HER-2 and anti–HER-2 Targeted Therapies
Anjali Jain, Ronald L. Shazer, Isett Laux, Jeffrey S. Ross, and David B. Agus
Chapter 16 Epidermal Growth Factor Receptor and Other Growth Factors and Receptors
Begoña Mellado, Joan Carles, Jeffrey S. Ross, and Joan Albanell
Chapter 17 Proteases: Targets of Tumor Invasion and Metastasis
Christopher S. Foster and Christine Gosden
Chapter 18 Angiogenesis and Angiogenesis Inhibitors: Applications in Adenocarcinoma of the Prostate
Edwin M. Posadas and William L. Dahut
Chapter 19 Cell Adhesion Molecules in Prostate Cancer
Kenneth A. Iczkowski and Christopher S. Foster
Chapter 20 Cell Survival, Apoptosis, and Proapoptotic Therapies
Helgi van de Velde, Jeffrey S. Ross, and Michel Janicot
Chapter 21 Oncogenes
Joanne Edwards and John M. S. Bartlett
Chapter 22 p53 and Tumor Suppressor Genes in Prostate Cancer
Jeffrey S. Ross, Andre M. Oliveira, Jonathan A. Fletcher, Scott E. Eggener, and Carlos Cordon-Cardo
Chapter 23 Ubiquitin Pathway and Proteasome Inhibitors
Helgi van de Velde and Jeffrey S. Ross
Chapter 24 Significance of DNA Methylation in Prostate Cancer Initiation and Progression
Christopher S. Foster and Samantha J. Ireland
Chapter 25 Bioinformatics, Computational Biology, and Morphometrics
Olivier Saidi and David A. Verbel
Chapter 26 Prostate-Specific Membrane Antigen and Other Cell Surface Protein Targets for Antibody-Based Therapeutics and Immunotherapy in Prostate Cancer
Jeffrey S. Ross, Karen E. Gray, Iain Webb, Gary S. Gray, Mark Rolfe, David P. Schenkein, David M. Nanus, Mathew I. Milowski, and Neil H. Bander
Chapter 27 Gene Therapy and Immunotherapy for Prostate Cancer
Laura K. Aguilar, Douglas J. Jolly, and Estuardo Aguilar-Cordova
Chapter 28 Pharmacogenomics and Pharmacogenetics in Prostate Cancer
Jeffrey S. Ross, W. Fraser Symmans, Lajos Pusztai, and Gabriel N. Hortobagyi
Chapter 29 Functional and Molecular Imaging of Prostate Cancer
Neeta Pandit-Taskar and Chaitanya R. Divgi
Chapter 30 Evaluation and Assessment of Molecular Markers and Their Translation Into Clinical Practice
Michael W. Kattan
Chapter 31 Regulatory Aspects and Implications of Molecular Testing in the United States
Robert G. Pietrusko
Index
