Preface

Acknowledgements  

SECTION I.    INTRODUCTION

1.       Toxicology and Its Roots as a Science  

2.       Chemical Properties and Information Resources on Hazardous Chemicals

3.       Toxicity and the Factors That Modify Toxic Responses

4.       Biological Poisons: Plant and Animal Toxins 

5.       Environmental Pollutants and Their Fate  

SECTION II.  TOXICOLOGY PRINCIPLES

6.       Dose and Response

7.    Absorption of Toxicants and Models of Disposition

8.       Distribution, Storage, and Elimination of Toxicants 

9.       Biotransformation

10.      Chemical-Induced Mutagenesis

11.   Chemicals and Cancer

SECTION III.  SYSTEMIC TOXICITY

12.   Role of Immune System   

13.   Skin                                                   

14.   The Liver and Kidneys                                              

15.   The Cardiovascular System

16.   The Respiratory System

17.   The Nervous System                                   

SECTION IV. TOXICOLOGY PRACTICE

18.   The Practice of Toxicology

19.   Regulatory Considerations

20.   Toxicity Testing

21.   Use and Limitations of Product Labeling for Public Safety

22.   Toxicology Principles in the Management of Acute Poisonings

23.   Risk Assessment and the Perception of Risk

24.   Making Informed Decisions

Glossary